Paper Trail Health

Health Propaganda, Exposed

Guideline thresholds & controversial drugs · Published 2019-03-07 · By Henry Rearden

How 'prediabetes' grew: Science traces industry money behind the expanded definition

Source: Charles Piller, Science (AAAS), March 7, 2019

Before you act: Don't stop, replace, or delay any treatment without talking to your doctor.

“You have a combination of two forces. One is to expand the definition of disease ... And second, direct endorsement of specific interventions that [guideline authors] have direct conflicts of interest with.”

Evidence level

Investigative journalism (interviews, payment records, published studies). Not a clinical study.

Funding

"This story was supported by the Science Fund for Investigative Reporting" (donor-funded).

What was published

An investigation of how the American Diabetes Association broadened prediabetes criteria and of payments to guideline authors.

What it shows

ADA "ratcheted down its prediabetes A1c threshold from 6.1% to 5.7%," creating "about 72 million potential new prediabetes patients in the United States alone." "Seven of the 14 ADA experts got between $41,000 and $6.8 million between mid-2013 and 2017 from makers of diabetes drugs or candidate prediabetes medicines or devices." ADA says it "has received $18 million to $27 million annually from drug companies."

What it does not show

Payments do not prove that any recommendation was changed because of money; one panelist told Science that payments "did not influence him," and ADA said funders have no influence over "the final outcome."

Documented counterpoints

ADA's chief scientific officer said evidence favored the lower threshold and that prediabetes is a "continuum of risk."

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Paper Trail Health summarizes published studies, case reports, court filings and journalism for general information. It is not medical, legal or investment advice. Summaries quote the sources; a source's statements are its authors', not findings of this site. Don't stop, replace, or delay treatment without your doctor. Always read the linked original. See Standards & corrections and Disclaimer.