Paper Trail Health

Health Propaganda, Exposed

Peptides & SARMs

Unapproved research peptides such as BPC-157, SARMs such as ostarine and RAD-140, and MK-677.

Don't stop, replace, or delay any treatment without talking to your doctor.

Peptides & SARMs · 2025-12-11 · Guardian Australia (independent journalism), December 11, 2025

BPC-157 sold online: clinics let users 'add to cart' unapproved peptides before seeing a doctor

"All allowed us to immediately browse and 'add to cart' injectable peptides that have not been approved by the TGA ... before speaking with a medical practitioner." It describes BPC-157 as having "been investigated for w…
Peptides & SARMs · 2025-09-01 · Edwin Lee, MD & Kailynd Burgess, Alternative Therapies in Health and Medicine, 2025

BPC-157 by IV: two-person safety pilot at a Florida clinic

"The infusions of BPC-157 resulted in no measurable effects on the tested biomarkers of the heart, liver, kidneys, thyroid, or blood glucose levels ... with no side effects reported."…
Peptides & SARMs · 2024-03-29 · Evexias Medical Centers et al. v. FDA, No. 4:24-cv-00293 (N.D. Tex., filed Mar. 29, 2024); Alliance for Pharmacy Compounding news, Sept 2024

Peptides: clinics and a compounder sued over CJC-1295, ipamorelin and others being put on a 'significant safety risk' list without advisory review

Plaintiffs argued the peptides were moved without advisory-committee review or notice-and-comment. A settlement led to advisory committee meetings in October and December 2024 to review four peptides.…
Peptides & SARMs · 2021-07-01 · Edwin Lee, MD & Bradley Padgett, Alternative Therapies in Health and Medicine, 2021

BPC-157 knee injections: retrospective phone survey of 16 clinic patients

"Of the 16 patients, 12 had received only BPC 157 ... 11 of the 12 patients (91.6%) had significant improvement in knee pain." "Overall, 14 of 16 patients (87.5%) had relief of their knee pain."…
Peptides & SARMs · 2013-08-19 · GTx, Inc. press release (Business Wire), Aug 19, 2013, via Fierce Biotech

SARMs: enobosarm's two phase 3 trials in lung-cancer muscle wasting missed their agreed endpoints

The trials "failed to meet the overall criteria for the co-primary responder endpoints of lean body mass and physical function." An exploratory analysis showed a "consistent effect on LBM" in both trials; stair-climb res…
Peptides & SARMs · 2011-08-02 · Dalton et al. (GTx, Inc.), Journal of Cachexia, Sarcopenia and Muscle, 2011

SARMs: company trial found enobosarm (ostarine) added 1.3 kg lean mass in older adults over 12 weeks

At 3 mg, participants gained "a statistically significant (P < 0.001) average of 1.3 kg" of lean mass versus placebo, with improved stair-climb power (P = 0.013). "No SAEs were reported."…
Peptides & SARMs · 2010-11-09 · Adunsky et al., Archives of Gerontology and Geriatrics 53(2):183-9, 2011 (Merck-sponsored)

MK-677: Merck's ibutamoren raised IGF-1 in hip-fracture patients, but the trial was stopped over heart failure

IGF-1 rose by 51.4 ng/ml versus placebo; gait speed improved (p = 0.011) and there were fewer falls (p = 0.096, not significant).…
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