Paper Trail Health

Health Propaganda, Exposed

Sold as safe · Published 2008-04-16 · By Henry Rearden

Vioxx: court documents describe ghostwritten reviews signed by recruited academics

Source: Ross, Hill, Egilman & Krumholz, JAMA, 2008

Before you act: Don't stop, replace, or delay any treatment without talking to your doctor.

“Recruited authors were commonly the sole author on the manuscript and offered honoraria for their participation.”

Evidence level

Case-study review of about 250 court documents from rofecoxib litigation plus 96 published articles.

Funding

Funding section not accessible to us; several authors served as plaintiffs' consultants in Vioxx litigation (see BMJ 2007 disclosure).

What was published

"Court documents originally obtained during litigation related to rofecoxib against Merck & Co Inc," created mostly 1996–2004.

What it shows

Documents describe "Merck marketing employees developing plans for manuscripts, contracting with medical publishing companies to ghostwrite manuscripts, and recruiting external, academically affiliated investigators to be authors." Only "50% (36 of 72) of review articles" disclosed Merck sponsorship or author compensation, versus 92% of trial articles.

What it does not show

It does not show the published data were false; it concerns authorship and disclosure practices in one company's documents.

Documented counterpoints

Merck disputed the characterization at the time, saying outside authors had meaningful roles.

Source link

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Paper Trail Health summarizes published studies, case reports, court filings and journalism for general information. It is not medical, legal or investment advice. Summaries quote the sources; a source's statements are its authors', not findings of this site. Don't stop, replace, or delay treatment without your doctor. Always read the linked original. See Standards & corrections and Disclaimer.